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目的:探讨前列地尔联合多巴胺治疗急性肾功能衰竭的临床疗效。方法:将46例急性肾功能衰竭患者随机分为观察组和对照组各23例,观察组给予前列地尔联合多巴胺治疗,对照组仅给予多巴胺治疗,比较2组患者的临床疗效。结果:观察组患者的总有效率约为95.66%,对照组患者的总有效率约为69.57%,观察组显著高于对照组,2组比较,差异具有统计学意义(p<0.05)。结论:前列地尔联合多巴胺治疗急性肾功能衰竭的临床效果显著,值得临床推广应用。
Objective: To investigate the clinical efficacy of alprostadil combined with dopamine in the treatment of acute renal failure. Methods: Forty-six patients with acute renal failure were randomly divided into observation group (23 cases) and control group (23 cases). The observation group was treated with alprostadil plus dopamine. The control group received only dopamine treatment. The clinical efficacy was compared between the two groups. Results: The total effective rate was 95.66% in the observation group and 69.57% in the control group. The observation group was significantly higher than the control group. The difference was statistically significant (P <0.05). Conclusion: Alprostadil combined with dopamine in the treatment of acute renal failure has significant clinical effect and is worthy of clinical application.