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目的:通过参与临床药学实践较长时间后,提出一些商榷性的探索,供参考以利于提高合理用药评价的科学性和有效性。方法:总结分析目前中小医院在开展合理用药调研实践中,存在一些影响合理用药评价标准的有效性问题。结果:临床药师与临床医师在某些临床个案病例中存在着药物治疗临床思维角度不同,对专业治疗指南诠释观点不同,对某些药物的合理用药评价结论的争议屡有发生。结论:鉴于合理用药的评价标准的难度和复杂性,及临床治疗进展的时效性,提示临床合理用药评价的有效性仍然是一个值得重视的实际问题。但只要以临床循证医学证据为药物治疗的评价基石,全面掌握病情,患者和药物的情况,因病制宜,因人制宜,制定一个合理精密给药方案,才能提高合理用药评价标准的有效性,促使临床药学朝着更高层次的发展。
OBJECTIVE: To put forward some deliberative explorations through participation in clinical pharmacy practice for a long period of time for reference to improve the scientificness and effectiveness of rational drug evaluation. Methods: To summarize and analyze the validity of small and medium-sized hospitals in conducting research on rational drug use, there are some problems affecting the evaluation criteria of rational drug use. Results: Clinical pharmacists and clinicians in different clinical cases have different clinical thinking perspectives and interpretations of professional treatment guidelines. Controversies over the rational drug evaluation conclusion of some drugs have occurred frequently. Conclusion: In view of the difficulty and complexity of the evaluation criteria of rational drug use and the timeliness of the progress of clinical treatment, it is still a practical issue worthy of attention to suggest that the validity of clinical rational drug evaluation. However, as long as clinical evidence-based medical evidence for the evaluation of the cornerstone of drug treatment, a comprehensive grasp of the disease, patients and drugs, due to illness, appropriate measures to develop a reasonable and precise dosing regimen in order to improve the rational use of drug evaluation criteria Effectiveness, to promote clinical pharmacy towards a higher level of development.