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目的:观察补阳还五汤治疗肾病综合征(NS)高凝状态的临床疗效。方法:中西组在运用西药常规治疗外,加服补阳还五汤并以口服双嘧达莫,洛伐他汀为对照组。观察两组疗效及服药前后血液流变学、血脂分析的变化及三年随访结果,并进行比较。结果:中西组(38例)愈显率(94.7%),对照组(34例)愈显率(91.2%),两组比较有显著性差异(P<0.05);中西组在改善血液高流变、降低三年复发率方面均优于对照组,而降脂水平与对照组接近。结论:补阳还五汤不仅可以良好地降低肾病综合征中出现的高凝状态,对NS的整个病程发展和远期疗效也有肯定的作用
Objective: To observe the clinical curative effect of Buyang Huanwu decoction in treating hypercoagulable state of nephrotic syndrome (NS). METHODS: In the western and western groups, after routine treatment with western medicine, Bu Yang Huan Wu Decoction was added and oral dipyridamole and lovastatin were used as control groups. Observe the effects of the two groups and the changes of blood rheology and blood lipid analysis before and after taking the drug and three-year follow-up results, and compare them. RESULTS: The Chinese and Western group (38 cases) had a clearer rate (94.7%), and the control group (34 cases) had a more obvious rate (91.2%). There was a significant difference between the two groups (P<0.05); The group was better than the control group in improving blood rheology and reducing the recurrence rate for three years, and the lipid-lowering level was similar to the control group. Conclusion: Buyang Huanwu Decoction can not only reduce the hypercoagulable state in nephrotic syndrome, but also have a positive effect on the overall course of development and long-term efficacy of NS.