免疫疗法治疗疱疹感染,开始用牛痘苗,据报告有好处,但缺乏对照。1959年Kern等报告,活疫苗或热灭活的疫苗对疱疹的复发率无差异,但2组均有明显的进步,可能这2种疫苗刺激了免疫机制。由于牛痘苗对防止疱疹复发的疗效可疑,而且对淋巴瘤等患者可导致严重的偶或致死的感染,故不应再用牛痘接种来预防疱疹的复发。 Immunotherapy to treat herpes infections and start vaccination with vaccinia is reported to be beneficial, but lacking of controls. In 1959, Kern et al. Reported that there was no difference in the relapse rate of herpes between the live vaccine and the heat-inactivated vaccine, but there were significant improvements in both groups. It may be that the two vaccines stimulate the immune mechanism. Vaccination should not be used to prevent the recurrence of herpes due to the suspicion of a curative effect of preventing vaccination against herpes recurrence and the potential for even or fatal infections in patients with lymphoma.