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本文报道自1964～1982年收治的18例小儿纵隔交惑神经源性肿瘤(神经母细胞瘤12例,神经节母细胞瘤4例,神经节细胞瘤2例),均位于后纵隔。呼吸道及神经压迫为常见症状,术前出现Horner征预示恶性。手术切除12例,本组神经母细胞瘤五年生存率25%。未行手术、单用化疗及Ⅲ、Ⅳ期病例均死亡。生存者均为2岁以下,Ⅰ、Ⅱ期和肿瘤全部切除的病例。强调早期手术,术后坚持化疗和放疗可提高生存率。神经母细胞瘤因具有自然消退特性,不能轻易放弃治疗。
This article reports 18 cases of pediatric mediastinal confusion of neurogenic tumors (neuroblastoma 12 cases, ganglioneuroblastoma 4 cases, ganglioneuroma 2 cases), all from 1964 to 1982, were located in the posterior mediastinum. Respiratory and nerve compression as a common symptom, preoperative Horner sign indicates malignancy. Surgical resection in 12 cases, the group of neuroblastoma five-year survival rate of 25%. No surgery, chemotherapy alone and Ⅲ, Ⅳ cases were dead. Survivors were under 2 years of age, Ⅰ, Ⅱ and tumor resection of all cases. Emphasis on early surgery, postoperative adherence to chemotherapy and radiotherapy can improve survival. Neuroblastoma can not give up treatment easily because of its natural extinction.