成骨细胞是骨形成的主要功能细胞,负责骨基质的合成、分泌和矿化。骨组织始终在不断地进行着重建,骨重建过程包括破骨细胞贴附在旧骨区域,分泌酸性物质溶解矿物质,分泌蛋白酶消化骨基质,形成骨吸收陷窝,而后成骨细胞移行至被吸收部位,分泌骨基质,骨基质矿化而形成新骨。破骨与成骨过程的平衡维持着人体正常骨量的代谢。 Osteoblasts are the major functional cells for bone formation and are responsible for the synthesis, secretion and mineralization of bone matrix. Bone tissue has been continuously rebuilt. The process of bone remodeling includes the attachment of osteoclasts to the old bone area, the secretion of acidic substances to dissolve the minerals, the secretion of protease to digest the bone matrix, the formation of bone resorption lacunae, and subsequent osteoblast migration to Absorption site, secretion of bone matrix, bone matrix mineralization and the formation of new bone. The balance of osteoclasts and osteoblasts maintains the metabolism of normal bone mass in the body.