论文部分内容阅读
目的探讨中青年脑梗死发病的相关因素。方法选择绍兴文理学院附属医院2010年1月—2014年10月35~45岁脑梗死住院患者105例为脑梗死组,同期体检且无神经症状的正常中青年110人为对照组,收集两组一般资料、实验室检测结果及颈动脉超声结果等资料,分析中青年脑梗死相关因素。结果多因素Logistic回归分析显示,高血压病史、糖尿病病史、脂代谢紊乱、吸烟史、肥胖、颈动脉斑块、高半胱氨酸血症和抗心磷脂抗体阳性是中青年脑梗死的独立危险因素,其OR值分别为14.614、5.129、44.970、26.180、45.196、258.786、14.585和5.145。结论高血压、糖尿病、脂代谢紊乱、吸烟、肥胖、颈动脉斑块、高半胱氨酸血症、抗心磷脂抗体阳性与中青年脑梗死发病密切相关,应积极预防与控制。
Objective To explore the related factors of cerebral infarction in young and middle-aged people. Methods Select the hospital of Shaoxing University of Arts and Sciences from January 2010 to October 2014 105 hospitalized patients aged 35-45 cerebral infarction as cerebral infarction group, the same period physical examination without neurosis in 110 normal young and middle-aged control group were collected two groups Data, laboratory test results and carotid ultrasound results and other data, analysis of young and middle-aged cerebral infarction related factors. Results Multivariate logistic regression analysis showed that hypertension history, history of diabetes mellitus, lipid metabolism disorders, smoking history, obesity, carotid artery plaque, homocysteinemia and anticardiolipin antibody were independent risk of middle-aged and young cerebral infarction Factors, the OR values were 14.614,5.129,44.970,26.180,45.196,258.786,14.585 and 5.145 respectively. Conclusions Hypertension, diabetes, dyslipidemia, smoking, obesity, carotid artery plaque, hypercysteinemia and anticardiolipin antibodies are closely related to the pathogenesis of middle-aged and young cerebral infarction, and should be actively prevented and controlled.