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目的探讨新发DM患者慢性并发症的分布状况。方法对餐后2小时血糖>120mg/dL的882例患者进行OGTT ,并对329例新发DM患者进行病史追问、血压测量、检查眼底、留2小时尿用RIA法测尿Alb排泄率。结果(1)329例新发DM中合并高血压者99例 ,占30 % ;合并神经病变者(肢麻)47例占14.2 %;尿Alb排泄率>20μg/min者(即DN)38例 ,占11.5 %。眼底视网膜病变Ⅰ～Ⅲ期改变17例 ,出现心梗或心绞痛病史者15例 ,发生脑卒中者11例。(2)OGTT结果示FBS<7.8mmol/L,PBS≥11.1mmol/L者196例占59.5 %。结论新发DM的并发症发病率相当高 ,依次为高血压、神经病变、肾病和糖尿病眼底视网膜病变。因此 ,加强糖尿病流行病学调查和糖尿病高危人群的普查 ,早期诊断是预防其并发症的主要措施。
Objective To investigate the distribution of chronic complications in newly diagnosed DM patients. Methods OGTT was performed on 882 patients with postprandial blood glucose >120mg/dL for 2 hours, and 329 patients with newly diagnosed DM were asked about history, blood pressure measurement, fundus examination, and urine retention for 2 hours. Urinary Alb excretion rate was measured by RIA. RESULTS: (1) Among 329 cases of new-onset DM, 99 cases were hypertensive patients with hypertension, accounting for 30%; 47 cases with neurological disorder (limb anesthesia) accounted for 14.2%; 38 cases with urinary Alb excretion rate >20μg/min (namely DN). , accounting for 11.5%. There were 17 cases of retinal lesions in stage I to III, 15 cases of history of myocardial infarction or angina, and 11 cases of stroke. (2) OGTT results showed that FBS <7.8 mmol / L, PBS ≥ 11.1 mmol / L, 196 cases accounted for 59.5 %. Conclusion The incidence of complications of new-onset DM is quite high, followed by hypertension, neuropathy, nephropathy, and diabetic retinopathy. Therefore, to strengthen the diabetes epidemiological survey and the general survey of high-risk groups of diabetes, early diagnosis is the main measure to prevent their complications.