本文测定96例新生儿感染患儿血清白细胞介素-8(IL-8)和粒细胞集落刺激因子(G-CSF),并与正常新生儿对照组比较。结果表明:感染急性期IL-8与G-CSF均高于恢复期及对照组,对照组与恢复期间无显著差异。此外,中性粒细胞计数与G-CSF存在正相关,而与IL-8无相关性。本文结果提示:IL-8和G-CSF作为炎症介质参与了新生儿感染疾病过程,是反映新生儿感染的重要指标。 In this paper, serum interleukin-8 (IL-8) and granulocyte-colony stimulating factor (G-CSF) in 96 neonates were measured and compared with normal neonates control group. The results showed that the levels of IL-8 and G-CSF in the acute phase were higher than those in the recovery phase and the control group, while there was no significant difference between the control group and the recovery phase. In addition, neutrophil count was positively correlated with G-CSF but not with IL-8. The results suggest that: IL-8 and G-CSF as inflammatory mediators involved in the process of neonatal infectious diseases, is an important indicator of neonatal infection.