[问]长期应用链霉素,可能损害第八对脑神经,而对其他神经则无明显损害,其机制如何?怎样治疗? (33766部队卫生队李和林) [答]链霉素由于生产技术关系,目前尚不能完全消除杂质,如甲醛链霉胍、二链霉胺等。长期大量应用,可能发生毒性反应,如口麻,眩晕,听力减退等。关于链霉素对第八对脑神经的损害问题,其机制不完全清楚。有人认为,与药物的亲和性有关。有人认为对内耳神经的损害有关。北京市耳鼻 [Q] Long-term use of streptomycin, may damage the eighth pair of cranial nerves, while no significant damage to other nerves, the mechanism and how? How to treat? (33766 Force Health Team Li and Lin) [Answer] Streptomycin due to production technology , At present can not completely eliminate impurities, such as formaldehyde streptavidin, two streptomycin and so on. Long-term large-scale application, toxic reactions may occur, such as mouth, dizziness, hearing loss and so on. About streptomycin damage to the eighth pair of cranial nerves, the mechanism is not fully understood. Some people think that, with the affinity of the drug. Some people think that the damage to the inner ear nerve. Beijing ears