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目的探讨缺血性脑血管病患者颈动脉粥样硬化斑块与其他危险因素的关系。方法对240例缺血性脑血管病患者及142例健康体检者进行彩色多普勒超声检测颈动脉内-中膜厚度(IMT)、斑块数和性状及血生化检查,包括总胆固醇(CH)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL)、低密度脂蛋白胆固醇(LDL)、血浆肌酐、纤维蛋白原(FIB)、血小板聚集度(PAG)。结果缺血性脑血管病组颈内动脉粥样斑块77.5%与对照组21.13%比较差异有统计学意义(P<0.01)。有高血压、糖尿病更易引起颈动脉粥样硬化(P<0.01)。结论颈动脉粥样硬化与缺血性脑血管病关系密切,高血压、糖尿病在斑块形成中起重要作用。而甘油三酯、总胆固醇、低密度脂蛋白胆固醇也影响动脉斑块的形成。
Objective To investigate the relationship between carotid atherosclerosis plaque and other risk factors in patients with ischemic cerebrovascular disease. Methods 240 cases of ischemic cerebrovascular disease and 142 healthy subjects were examined by color Doppler ultrasonography for carotid intima - media thickness (IMT), plaque number and traits and blood biochemical tests, including total cholesterol (CH TG, HDL, LDL, FIB and PAG were measured. Results There was significant difference in 77.5% of internal carotid artery atherosclerotic plaque in ischemic cerebrovascular disease group and 21.13% in control group (P <0.01). Have high blood pressure, diabetes more likely to cause carotid atherosclerosis (P <0.01). Conclusion Carotid atherosclerosis is closely related to ischemic cerebrovascular disease. Hypertension and diabetes play an important role in plaque formation. Triglycerides, total cholesterol and low-density lipoprotein cholesterol also affect the formation of arterial plaque.