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本文报告使用~(131)I—MG_7—McAb对17例胃癌病人进行放射免疫显像的临床应用。静脉注射~(131)I—MG_7—McAb后,4小时肿瘤部位出现放射性浓聚,24小时即可获得满意的图像。本组资料表明:原发灶阳性率为82.4%,转移灶阳性率为33.3%。所显示的胃癌原发灶与转移灶部位与手术对照基本一致。说明放射免疫显像不但可以定性而且具有显示肿瘤位置、大小、形态和有无转移灶的优点,这些信息对肿瘤的诊断、治疗计划及疗效观察具有临床实用价值。
This article reports the clinical application of ~(131)I-MG_7-McAb in radioimmunoimaging of 17 patients with gastric cancer. After intravenous injection of 131I-MG_7-McAb, radioactivity concentrated at the tumor site within 4 hours and a satisfactory image was obtained within 24 hours. The data in this group showed that the positive rate of primary foci was 82.4% and the positive rate of metastases was 33.3%. The primary gastric cancer and metastatic sites shown were basically consistent with the surgical control. It shows that radioimmunoimaging imaging can not only be qualitative but also has the advantages of displaying tumor location, size, morphology and whether there is metastasis. These information have clinical practical value for the diagnosis, treatment planning and curative effect observation of the tumor.