【摘 要】
：
Although Asia has a very low incidence of prostate cancer in comparison with other Asian countries,Japan has one of the highest incidence (30.4 per 100 000) and mortality rates (5 per 100 000) from prostate cancer,according to the 2012 GLOBOCAN estimates.
【机 构】
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Monash Medical Centre, Melbourne, Australia;University Hospitals Bristol Trust,Bristol, UK
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Although Asia has a very low incidence of prostate cancer in comparison with other Asian countries,Japan has one of the highest incidence (30.4 per 100 000) and mortality rates (5 per 100 000) from prostate cancer,according to the 2012 GLOBOCAN estimates.1 Kitagawa et al.2 conducted a retrospective analysis of the populationbased trends of prostate-specific antigen (PSA) screening conducted in men,between the ages of 54 and 69 years in Kanazawa city,which comprises of about a third of the Japanese population.In this annual screening program,they demonstrated a decreasing trend in the median serum PSA levels in men diagnosed with prostate cancer,when comparing the 5 year periods of 2000-2005 and 2006-2011,with a corresponding increase in low stage disease (T1c).However,no changes in PSA levels were detected in men without prostate cancer during these 5 years periods.
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