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目的:观察醒脑静注射联合脑神经营养剂治疗急性脑梗死的临床疗效。方法:选取76例急性脑梗死患者,以随机抽签法分为对照组和观察组各38例,对照组单纯采用脑神经营养剂治疗,观察组在对照组用药基础上加用醒脑静注射液治疗。比较2组临床疗效,治疗前后脑电图异常程度、美国国立卫生院神经功能缺损评分(NIHSS评分)及血液流变学指标的变化。结果:治疗2周后,观察组临床疗效总有效率高于对照组(P<0.05)。2组脑电图异常程度均较治疗前改善,观察组优于对照组(P<0.05);2组NIHSS评分均较治疗前降低(P<0.05),观察组NIHSS评分低于对照组(P<0.05);2组血液流变学指标水平均低于治疗前(P<0.05),观察组各指标水平均低于对照组(P<0.05)。结论:醒脑静注射联合脑神经营养剂治疗急性脑梗死可有效消除脑电图异常、降低神经功能损伤程度,并有助于改善血液流变学,疗效确切。
Objective: To observe the clinical effect of Xingnaojing injection combined with neurotrophic agent in the treatment of acute cerebral infarction. Methods: Seventy-six patients with acute cerebral infarction were randomly divided into control group and observation group, with 38 cases in each group. The control group was treated with brain neurotrophic agent alone. In the control group, Xingnaojing injection treatment. The clinical efficacy, EEG abnormalities before and after treatment, NHSS scores and hemorrheological indexes of the two groups were compared. Results: After 2 weeks of treatment, the total effective rate in clinical observation group was higher than that in control group (P <0.05). The EEG abnormalities in both groups were improved compared with before treatment, and the observation group was better than the control group (P <0.05). The NIHSS scores of the two groups were lower than those before treatment (P <0.05), and the NIHSS scores of the observation group were lower than those of the control group <0.05). The levels of hemorheology indexes in both groups were lower than those before treatment (P <0.05), and the levels of each index in the observation group were lower than those in the control group (P <0.05). Conclusion: Xingnaojing injection combined with neurotrophic agents in the treatment of acute cerebral infarction can effectively eliminate the abnormal EEG, reduce the degree of neurological impairment, and help to improve the blood rheology, the exact effect.