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目的观察非诺贝特辅治老年性高脂血症性胰腺炎的临床疗效。方法将70例老年性高脂血症性胰腺炎患者随机分为A组和B组各35例。B组患者采用常规抗胰腺炎治疗,A组在B组治疗的基础上加用非诺贝特,比较2组患者治疗前后三酰甘油(TG)、血淀粉酶(AMY)以及血钙(Ca)水平变化。结果 2组患者的TG、AMY较治疗前明显下降(P<0.05);且A组患者的TG、AMY水平显著低于B组(P<0.05);2组患者血液中Ca水平与治疗前对比差异无统计学意义(P>0.05)。结论老年性高脂血症性胰腺炎患者具有病情复杂的特点,治疗高脂血压胰腺炎在常规治疗的基础上加用非诺贝特,疗效更为显著。
Objective To observe the clinical efficacy of fenofibrate in the treatment of senile hyperlipidemic pancreatitis. Methods Seventy patients with senile hyperlipidemic pancreatitis were randomly divided into A group and B group, 35 cases each. Patients in group B were treated with conventional anti-pancreatitis. Group A was treated with fenofibrate on the basis of group B. The levels of triglyceride (TG), amylase (AMY) and serum calcium Change in level. Results The levels of TG and AMY in two groups were significantly lower than those before treatment (P <0.05). The levels of TG and AMY in group A were significantly lower than those in group B (P <0.05). The levels of Ca in the two groups were significantly lower than those before treatment The difference was not statistically significant (P> 0.05). Conclusions Elderly patients with hyperlipidemic pancreatitis have the characteristics of complicated diseases. The treatment of hyperlipidemic pancreatitis is more effective than fenofibrate on the basis of routine treatment.