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目的探讨尿微量白蛋白(尿mALB)与妊娠期高血压疾病患者早期肾损害的关系,评价临床诊断价值。方法采用免疫散射比浊法检测70例孕25～42周孕妇尿微量白蛋白(尿蛋白定性均为阴性),其中35例妊娠期高血压孕妇作为观察组,另35例为我校进行健康体检的健康育龄妇女为对照组。结果观察组尿微量白蛋白(26.01±7.28)mg/L,超过参考值阳性率60.00%。对照组尿微量白蛋白(8.17±2.98)mg/L,超过参考值阳性率10.00%。两组统计学差异均有统计学意义(P<0.05)。结论妊娠期高血压疾病早期肾损伤患者尿微量白蛋白明显升高,检测尿微量白蛋白可用于及早发现妊娠期高血压疾病的早期肾损伤,对及时干预,阻止病情发展有其重要的临床意义。
Objective To investigate the relationship between urinary microalbuminuria (MALB) and early renal damage in patients with hypertensive disorder complicating pregnancy and evaluate the value of clinical diagnosis. Methods Urine microalbuminuria (urinary protein was negative in 70 pregnant women with gestational age from 25 to 42 weeks) was detected by immunoturbid nephelometry. 35 pregnant women with gestational hypertension were regarded as the observation group and the other 35 were examined by our school Healthy women of childbearing age as the control group. Results Urine microalbuminuria (26.01 ± 7.28) mg / L in the observation group exceeded the reference value by 60.00%. Urine microalbumin in control group (8.17 ± 2.98) mg / L, exceeding the reference value of the positive rate of 10.00%. There was statistical significance between the two groups (P <0.05). Conclusions Urine microalbuminuria in patients with early renal injury of hypertensive disorder complicating pregnancy is obviously increased. Detection of urine microalbumin can be used to detect early renal injury of hypertensive disorder complicating pregnancy. It has an important clinical significance for prompt intervention and prevention of disease progression .