美国康奈尔大学医学院的研究人员发现一种称为侵袭素的蛋白质,有希望成为疫苗、治疗剂和基因治疗的载体。 研究人员在1993年克隆了表达侵袭素的结核杆菌基因,把它称为“分枝杆菌侵入”（MCE）基因,因为侵袭素能使结核杆菌侵入哺乳动物细胞。 到目前为止,研究人员已发现此蛋白能包被空心的胶乳珠,并使它们进入场体细胞。如果它含某一种治疗剂,这些“生物可降解”珠可作为第二保护层,保护治疗剂免受免疫应答的影响,同时也建立了一种持续释放的形式。据研究小组负责人Riley Researchers at Cornell Medical College in the US have discovered a protein called invasive protein that promises to be a vector for vaccines, therapeutics and gene therapy. The researchers cloned the Mycobacterium tuberculosis gene that expresses the invasive element in 1993, calling it a “mycobacterial invasion” (MCE) gene because invasive elements cause the M. tuberculosis to invade mammalian cells. So far, researchers have found that this protein can be coated hollow latex beads, and make them into the field cells. If it contains a certain therapeutic agent, these “biodegradable” beads act as a second protective layer, protecting the therapeutic from the effects of the immune response while also establishing a sustained release form. According to research team leader Riley