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目的分析河北省磁县2000-2002年恶性肿瘤生存情况,为肿瘤防治工作提供科学依据。方法对河北省磁县肿瘤登记处登记的2000-2002年发病的4 170例恶性肿瘤患者生存资料进行分析,采用Kaplan-meier法计算观察生存率(OSR),Ede-r I法计算相对生存率(RSR)。结果 2000-2002年河北省磁县共登记恶性肿瘤发病4 170例,发病率为218.58/10万;发病前10位的恶性肿瘤依次为食管癌、胃癌、肺癌、肝癌、结直肠癌、乳腺癌、神经系统恶性肿瘤、子宫恶性肿瘤、白血病和淋巴瘤,中位生存期依次为17、15、9、6、16、40、10、18、7和17个月;2000-2002年恶性肿瘤患者1~5年OSR分别为34.92%、26.86%、20.98%、16.95%和14.99%;恶性肿瘤患者1~5年RSR分别为36.61%、28.86%、23.43%、19.71%、18.18%;其中食管癌、结直肠癌、乳腺癌和子宫恶性肿瘤的5年RSR>20%;肺癌、肝癌和白血病的5年RSR<10%;不同性别、年龄、地区及病理类型恶性肿瘤患者的1~5年RSR差异均有统计学意义(P<0.01)。食管癌、胃癌、肺癌5年OSR分别为17.83%、15.69%和5.76%;食管癌、胃癌、肺癌5年RSR分别为21.65%、19.35%和7.23%。结论磁县人群恶性肿瘤生存率较低,主要影响因素为性别、年龄、地理分布和病理类型。
Objective To analyze the survival of malignant tumor from 2000 to 2002 in Cixian County, Hebei Province, and to provide a scientific basis for the prevention and treatment of cancer. Methods Survival data of 4 170 patients with malignant tumors from 2000 to 2002 registered in Cixian Cancer Registry of Hebei Province were analyzed. Survival rate (OSR) was calculated by Kaplan-Meier method and relative survival rate was calculated by Ede-r I method (RSR). Results A total of 4 170 malignant tumors were recorded in Cixian County of Hebei Province from 2000 to 2002, with an incidence rate of 218.58 / 100 000. The top 10 malignant tumors were esophageal cancer, gastric cancer, lung cancer, liver cancer, colorectal cancer, breast cancer , Malignant neoplasms, uterine malignancies, leukemias and lymphomas with a median survival of 17, 15, 9, 6, 16, 40, 10, 18, 7 and 17 months, respectively; The OSR of 1- 5 years were 34.92%, 26.86%, 20.98%, 16.95% and 14.99% respectively. The RSRs of patients with malignant tumors from 1 to 5 years were 36.61%, 28.86%, 23.43%, 19.71% and 18.18% 5-year RSR> 20% for colorectal, breast and uterine malignancies; 5-year RSR for lung, liver and leukemia <10%; 1 to 5 years for patients with different sexes, ages, regions and pathologies The differences were statistically significant (P <0.01). The 5-year OSR of esophageal cancer, gastric cancer and lung cancer were 17.83%, 15.69% and 5.76% respectively. The 5-year RSR of esophageal cancer, gastric cancer and lung cancer were 21.65%, 19.35% and 7.23%, respectively. Conclusion The survival rate of malignant tumors in Cixian population is low, the main influencing factors are gender, age, geographical distribution and pathological types.