论文部分内容阅读
纳洛酮 (Naloxone hydroohloride,商品 Narcan简称纳洛酮NX) ,化学结构与吗啡极为相似 ,能与阿片受体 (opiate recepor)产生特异性结合 ,其亲和力大于吗啡和脑啡肽 ,是阿片受体的纯拮抗剂。196 0年 Fishman首先合成了纳洛酮 (NX) ;美国于 1971年开始用于临床。国内 1983年由军
Naloxone hydroohloride (Naloxone NX) is chemically similar to morphine and can specifically bind to opiate receptors. Its affinity is greater than that of morphine and enkephalin. It is an opioid receptor Pure antagonist. Fishman first synthesized naloxone (NX) in 1960; the United States began clinical use in 1971. In 1983 by the army