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本文采用DE 52纯化单抗,胃蛋白酶消化,Sephacryl S300分离,制备MG_4 F(ab’)_2,用~(13)I标记,对8例胃癌病人进行了RII 初步研究。 胃癌病人均经胃镜及病理确诊。接受检查前1～2天先用复方碘溶液封闭甲状腺,注射~(131)I-MG_7 F(ab’)_2前先静脉滴注地塞米松2～4mg,再缓慢滴注~(131)I-MG_7 F(ab’)_2 66.6-
In this study, DE 52 purified monoclonal antibody was digested with pepsin and separated by Sephacryl S300 to prepare MG_4 F(ab’)_2 and labeled with ~(13)I. Eight cases of gastric cancer were studied by RII. Gastric cancer patients were confirmed by gastroscopy and pathology. One to two days before the examination, the thyroid gland was closed with compound iodine solution. Before intravenous injection of 131I-MG_7 F(ab’)2, 2-4 mg of dexamethasone was infused intravenously, followed by a slow instillation of 131I. -MG_7 F(ab’)_2 66.6-