华东师范大学生命医学研究所发现,中草药单体藤黄酸能通过抑制血管新生来抑制小鼠肿瘤。藤黄酸通过直接作用于血管内皮细胞受体2,引起细胞内多条信号途径变化,最终抑制血管新生,从而“饿死”肿瘤。用藤黄酸治疗的小鼠,其肿瘤基本处于休眠状态,小鼠生活正常;而未治疗的肿瘤迅速增大, The Institute of Life Medicine at East China Normal University found that gambogic acid, a Chinese herbal medicine, can inhibit mouse tumors by inhibiting angiogenesis. Gambogic acid acts directly on receptor 2 of the vascular endothelial cells, causing multiple signal pathway changes in the cells, ultimately inhibiting angiogenesis and thus starving the tumor. In the mice treated with gambogic acid, the tumors were basically dormant and the mice lived normal; while the untreated tumors increased rapidly.