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目的了解浙江省艾滋病病毒(HIV)感染再生育孕产妇特征和妊娠结局,为及时有效地开展艾滋病母婴传播阻断干预提供依据。方法收集2010—2014年浙江省预防艾滋病母婴传播直报系统HIV感染孕产妇个案资料,根据分娩情况分为初次生育孕产妇和再生育孕产妇,比较两组的人口学特征及妊娠结局。结果 2010—2014年浙江省累计报告孕产妇3 310 646人,确证HIV感染孕产妇920例,孕产妇HIV感染率为0.03%。其中再生育孕产妇463例,占50.33%;浙江省91个县(市、区)中有59个(64.84%)报告HIV感染再生育孕产妇,其中31个县(市、区)(34.07%)HIV感染再生育孕产妇比例为(1.98~8.45)/万。HIV感染再生育孕产妇年龄、少数民族比例、农民及家务待业比例、已婚比例、外地户籍比例、性伴HIV感染阳性比例及孕次均高于HIV感染初次生育孕产妇,而文化程度及孕前确证HIV感染比例均低于HIV感染初次生育孕产妇(均P<0.05)。HIV感染再生育和初次生育孕产妇死胎发生率分别为1.60%和0.75%,早产或低出生体重儿分别为8.51%和6.72%,差异均无统计学意义(P>0.05)。确证HIV感染婴儿5例,均来自HIV感染再生育孕产妇。结论浙江省HIV感染再生育孕产妇占HIV感染孕产妇的50.33%,具有年龄偏大、文化程度较低、外地户籍比例高等特征,所生育婴儿中有5例确证HIV感染。
Objective To understand the maternal characteristics and pregnancy outcome of HIV / AIDS infertility in Zhejiang Province and provide a basis for timely and effective intervention for preventing mother-to-child transmission of HIV. Methods The data of HIV-infected pregnant women in Zhejiang Province from 2010-2014 were collected. According to the status of childbirth, they were divided into first-time pregnant women and second-born pregnant women. The demographic characteristics and pregnancy outcomes were compared between the two groups. Results In 2010-2014, a total of 3 310 646 pregnant women were reported in Zhejiang Province. 920 HIV-infected pregnant women were confirmed. The HIV infection rate among pregnant women was 0.03%. Among them, 463 (50.33%) were maternity pregnant women and 59 (64.84%) pregnant women in 91 counties (cities and districts) in Zhejiang Province reported 31 pregnant women (34.07% ) The proportion of pregnant women with HIV infection and fertility was (1.98 ~ 8.45) / million. HIV infection reproductive age maternal age, ethnic minority, peasant and homework ratio, married ratio, the proportion of foreign household registration, sexual partner HIV positive rate and gestational age were higher than those of HIV-infected first-time pregnant women, while education and pre-pregnancy Confirmed that the proportion of HIV infection were lower than the number of HIV-infected first-time pregnant women (all P <0.05). The prevalence of HIV and reproductive and firstborn maternal stillbirth were 1.60% and 0.75%, respectively, and 8.51% and 6.72% for preterm and low birth weight infants, respectively, with no significant difference (P> 0.05). Confirmed 5 cases of HIV-infected infants, all from HIV infertility pregnant women. Conclusion Reproductive pregnant women with HIV infection in Zhejiang Province account for 50.33% of pregnant women with HIV infection. They have the characteristics of older age, lower education level and higher proportion of permanent residents in the field. Five of the infants were confirmed HIV infection.