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目的：分析非普拉宗治疗４种关节病变的疗效及不良反应。方法：１６家医院，按国际公认的诊断标准和疗效判断标准随机观察１０００例，其中类风湿关节炎５０５例，骨关节炎３１６例，风湿热１４７例，痛风关节炎３２例。非普拉宗用量０．２ｇ／次，ｐｏ，ｂｉｄ，４ｗｋ为一个疗程，开放式观察。结果：骨关节炎、类风湿关节炎、风湿热、痛风关节炎的总有效率分别为８２．０％，８４．０％，９６．６％，１００％。胃肠道不良反应率１２．６％，其余均较低。结论：国产非普拉宗的疗效可靠，药物不良反应发生率较低
Objective: To analyze the efficacy and adverse reactions of non-Pulazan in treating 4 kinds of joint diseases. Methods: Totally 16 hospitals were randomly selected according to internationally recognized diagnostic criteria and curative effect criteria. One hundred and five patients were randomly selected, including 505 rheumatoid arthritis, 316 osteoarthritis, 147 rheumatic fever and 32 gouty arthritis. Non-pravastatin dosage 0.2g / time, po, bid, 4wk for a course of treatment, open observation. Results: The total effective rates of osteoarthritis, rheumatoid arthritis, rheumatic fever and gouty arthritis were 82.0%, 84.0%, 96.6% and 100% respectively. Adverse gastrointestinal adverse reaction rate was 12.6%, the rest were lower. Conclusion: The efficacy of domestic non-Pulazan reliable, low incidence of adverse drug reactions