例1 女,16岁.因月经量增多,经期延长半年,近一个月突然有大出血伴烂肉样组织及下腹阵痛来诊。妇科检查:子宫如孕10周大小,活动,表面尚光滑,行诊断性刮宫术。病理报告:子宫内膜间质肉瘤,5天后做次广泛子宫切除术。病理检查 于宫腔后壁见-4.5cm×4cm×3cm之菜花状肿物,切面淡黄色,质细腻较软,镜下见大片弥漫性增生的子宫内膜间质瘤细胞,瘤细胞均匀,致密纺锤状或圆形(图1),瘤细胞核大、卵圆形、浓染,异型性显著,核分裂相18～24个/10HPF(图2),瘤组织有明显出血坏死。病理诊断:子宫内膜间质肉瘤(高度恶性)。例2 女,43岁.不规则阴道流血1年,下腹部痛疼。妇科检查:子宫增大如孕12周大小,质硬,表面凹凸不平.病理检查:子宫次全切除标本,子宫前壁明显增厚,有-7cm×5cm×3cm之杏黄色肿物,部分周围组织有分界而无包膜,质软,鱼肉状。镜下见子宫肌层平滑肌束间有弥漫性、浸润性生长的子宫内膜间质瘤细胞,核分裂相6～10个/10HPF,网织染色,显 Example 1 female, 16 years old due to an increase in menstrual flow, menstrual period extended six months, nearly a month suddenly had bleeding with rotten meat-like tissues and lower abdomen pain visit. Gynecological examination: 10 weeks pregnant uterus size, activity, the surface is still smooth, diagnostic curettage. Pathology report: Endometrial stromal sarcoma, 5 days after a wide range of hysterectomy. Pathological examination in the uterine cavity wall see -4.5cm × 4cm × 3cm of cauliflower-like tumor, section pale yellow, soft and delicate quality, microscopic see a large diffuse proliferative endometrial stromal tumor cells, tumor cells, Tight spindle or round (Figure 1), large tumor nuclei, oval, dense staining, significant atypia, mitotic phase 18 ~ 24 / 10HPF (Figure 2), tumor tissue was significantly hemorrhagic necrosis. Pathological diagnosis: endometrial stromal sarcoma (highly malignant). Example 2 female, 43 years old. Irregular vaginal bleeding for 1 year, lower abdominal pain. Gynecological examination: enlarged uterus, such as 12 weeks pregnant size, hard, uneven surface .Pathological examination: subtotal hysterectomy specimens, the anterior wall of the uterus was significantly thicker, -7cm × 5cm × 3cm apricot yellow mass, part of the surrounding Divide without tissue, soft, fishy. Microscope, see the myometrium between the smooth muscle bundles diffuse, invasive growth of endometrial stromal cells, mitotic phase 6 ~ 10 / 10HPF, reticular staining, was significantly