作者对101例年龄6周至13岁确诊为细菌性脑膜炎的患儿进行双盲对照地塞米松试验,将患儿随机分为地塞米松加头孢噻肟治疗组(52例)和安慰剂加头孢噻肟对照组(49例)。头孢噻肟每次50mg/kg,每6小时静注1次,每次10～15分钟,疗程7～10天或以上。地塞米松每次0.15mg/kg,每6小时1次,首次在头孢噻肟第1次用药前15～20分钟应用,共用4天。 The authors performed a double-blind controlled dexamethasone trial of 101 children aged 6 weeks to 13 years diagnosed with bacterial meningitis. The children were randomized to dexamethasone plus cefotaxime (52 patients) and placebo plus Cefotaxime control group (49 cases). Each cefotaxime 50mg / kg, intravenous injection once every 6 hours, each 10 to 15 minutes, 7 to 10 days or more course of treatment. Dexamethasone 0.15mg / kg every 6 hours for the first time in cefotaxime before the first 15 to 20 minutes of application, for 4 days.