蛋白质组学研究细胞内蛋白质组成及其活动规律是对不同时间和空间发挥功能的特定蛋白质群体的研究。通过比较分析不同条件蛋白质组的差异表达,着眼发现和鉴定出有差异的蛋白质或蛋白质群,即比较蛋白质组学。介绍比较蛋白质组学研究内容适用于比较蛋白质组学研究的相关技术及其在疾病研究中的应用进展。 Proteomics Research Intracellular protein composition and activity patterns are studies of specific protein populations that function at different times and spaces. By comparative analysis of differential expression of different conditions of the proteome, focusing on the discovery and identification of differentiated proteins or protein groups, that is, comparative proteomics. Introduction The comparative proteomics study is applicable to the comparative proteomics research and its application in disease research.