我院近2年收治2例轻型胰腺炎,因用5-Fu配氯霉索治疗,引起粒细胞减少,死于败血症,有深刻的教训,现报告如下。例1:女,19岁。突发上腹部持续性疼痛16小时。体检:不发热,巩膜不黄,左上腹压痛,无腹水征。血淀粉酶2100u,尿淀粉酶2515u。Hb 115g/L,WBC 9.6×10~9/L,N 0.83,L 0.17。B超提示胆道蛔虫及胰腺炎。1989年9月23日入院,用5-Fu500毫克十氯霉素750毫克,静脉滴入,每天一次,住院第4日血尿淀粉酶正常,有轻度 2 cases admitted to our hospital nearly 2 years of light pancreatitis, 5-Fu with chloramphenicol treatment, causing neutropenia, died of sepsis, there are profound lessons, are as follows. Example 1: Female, 19 years old. Sudden upper abdomen persistent pain for 16 hours. Physical examination: no fever, sclera is not yellow, left upper quadrant tenderness, no signs of ascites. Blood amylase 2100u, urinary amylase 2515u. Hb 115 g / L, WBC 9.6 × 10 9 / L, N 0.83, L 0.17. B ultrasound prompt biliary ascariasis and pancreatitis. September 23, 1989 admission, with 5-Fu500 mg of 10 mg chloramphenicol, intravenous infusion once a day, the first 4 days of hematuria amylase normal, mild