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目的:探讨中西医结合治疗早期糖尿病肾病的治疗效果。方法:选择2010年1月到2011年12月我院住院的71例早期糖尿病肾病患者,采用西医即口服卡托普利(25 mg/次,2次/d)和胰激肽原酶(240 U/次,3次/d)对症治疗37例为对照组,在西医治疗基础上加服自拟复方中药34例作为研究组。两组持续治疗12周。观察并比较两组的疗效,测定治疗前后尿素氮(BUN)、血肌酐(SCr),24 h尿蛋白定量的变化。结果:对照组的总有效率为82.8%,治疗组的总有效率为94.8%,两组相比,差异具有统计学意义(P<0.05);两组治疗后BUN,SCr,24 h尿蛋白定量降低均较明显,较治疗前相比差异具有统计学意义(P<0.05),与对照组比较,治疗组各指标的效果要明显优于对照组,差异显著,有统计学意义(P<0.05)。结论:中西医结合治疗糖尿病肾病的治疗效果显著,值得推广。
Objective: To explore the treatment of early diabetic nephropathy with integrated traditional Chinese and western medicine. Methods: A total of 71 patients with early diabetic nephropathy hospitalized in our hospital from January 2010 to December 2011 were enrolled in this study. They were treated with western medicine (captopril 25 mg twice daily and pancreatic kininogenase 240 U / times, 3 times / d) symptomatic treatment of 37 cases as the control group, based on the Western medicine plus serving 34 cases of compound traditional Chinese medicine as a research group. The two groups continued treatment for 12 weeks. The curative effect of the two groups was observed and compared, and the change of the blood urea nitrogen (BUN), serum creatinine (SCr) and 24 h urinary protein before and after treatment were measured. Results: The total effective rate of the control group was 82.8%, the total effective rate of the treatment group was 94.8%, the difference was statistically significant (P <0.05); The levels of BUN, SCr, 24h urinary protein (P <0.05). Compared with the control group, the effect of each index of the treatment group was significantly better than that of the control group, the difference was statistically significant (P < 0.05). Conclusion: The treatment of diabetic nephropathy with traditional Chinese and western medicine is effective and worthy of promotion.