新疆阿尔泰山生长的厚叶岩白菜系虎尔草科植物(Bergema Crassifolia(L)Firitsch),药用地上全草。其有效成份岩白菜素,经研究证明:与湖南矮地茶和云南岩白菜等植物中提到的岩白菜素是同一物质。新疆制药厂将岩白菜素制成片剂,用于临床,具有镇咳祛痰作用。但有关岩白菜素体内过程规律未见报道。因此,测定药物动力学参数,为选择剂型、改进工艺、临床 The thick-leaf white-crested Bergerian plant (Bergema Crassifolia (L) Firitsch) in the Altai Mountains of Xinjiang is used to medicinal plants. Its active ingredient, bergenin, has been studied and proved to be the same substance as bergenin mentioned in plants such as Hunan dwarf tea and Yunnan rock cabbage. Xinjiang Pharmaceutical Factory will make bergenin into tablets for clinical use with antitussive and expectorant effects. However, there are no reports on the in vivo process of bergenin. Therefore, the determination of pharmacokinetic parameters is to select the dosage form, improve the process, clinical