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目的:研究C反应蛋白定量测定在诊断细菌性肠炎的准确性,并对其进行评价。方法:选自我院自2012年3月到2012年11月经过病原学检查已经确诊为细菌性肠炎的患者66例作为治疗组,将另外经检测为腹泻患者的78例作为对照组,采用免疫比浊法分别测定治疗组和对照组的血清C反应蛋白的浓度,与阳性判断标准血清C反应蛋白8mg/L来分析血清C反应蛋白检测诊断细菌性肠炎的准确性。结果:治疗组血清C反应蛋白的浓度为(85.7±33.5)mg/L,在66例细菌性肠炎患者中有62例患者的血清C反应蛋白含量出现升高,对照组的血清浓度为(5.8±3.2)mg/L,对照组的78例患者中仅有9例患者的血清C反应蛋白浓度出现升高,分析统计两组患者的血清C反应蛋白浓度结果有明显差异(p<0.01),具有统计学意义。利用血清C反应蛋白检测细菌性肠炎的准确度为96.88%。结论:血清C反应蛋白定量检测诊断细菌性肠炎有较好的准确性,有一定的临床使用价值。
Objective: To study the accuracy of quantitative determination of C-reactive protein in the diagnosis of bacterial enteritis and to evaluate its value. Methods: Sixty-six patients with confirmed bacterial enteritis in our hospital from March 2012 to November 2012 were selected as the treatment group. Another 78 patients who were diagnosed as diarrhea were selected as the control group. The turbidimetric method was used to determine the concentration of serum C-reactive protein in the treatment group and the control group respectively. The positive serum C-reactive protein 8mg / L was used to analyze the accuracy of serum C-reactive protein in the diagnosis of bacterial enteritis. Results: Serum C-reactive protein level in the treatment group was (85.7 ± 33.5) mg / L, and the serum C-reactive protein level in 62 of 66 patients with bacterial enteritis increased, while the serum concentration of the control group was (5.8 ± 3.2) mg / L, only 9 of the 78 patients in the control group had elevated serum C-reactive protein levels. There was a significant difference (p <0.01) in the analysis of serum C-reactive protein concentrations between the two groups, has statistical significane. The accuracy of using serum C-reactive protein to detect bacterial enteritis was 96.88%. Conclusion: Quantitative detection of serum C-reactive protein in the diagnosis of bacterial enteritis has good accuracy and has certain clinical value.