男性工人胆固醇水平与总死亡率关系的定群随访研究

来源 :高血压杂志 | 被引量 : 0次 | 上传用户:niudaben
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
目的 :分析胆固醇与冠心病、脑血栓、脑出血、肿瘤、心脑血管疾病及肿瘤以外的其它疾病的关系。方法 :在 1974,1979,1980三个年份对北京某钢厂三个人群年龄在 18至 74岁 (平均 45 .3岁 )的 4814名男性工人进行了心脑血管疾病的基线调查 ,并测定了血清总胆固醇水平。随访终点为 1993年 ,平均随访 14.5年。将基线血清胆固醇水平按百分数的四分位数法分成四组。采用 L ogistic回归分析方法 ,控制变量为 :年龄、吸烟、饮酒、收缩压、舒张压等变量。结果 :共有 35 1名工人死亡。死亡原因分别是 ,冠心病 40名(11.4% ) ,脑血栓 2 3名 (6 .5 5 % ) ,脑出血 47名 (13.39% ) ,肿瘤 12 7名 (36 .18% ) ,其它疾病 114名 (32 .48% ) .疾病总死亡率与各组胆固醇呈 U 型关系。以最高胆固醇组做参照 ,L ogistic分析结果 :其它胆固醇组冠心病死亡率危险均小于最高组 ,从最低组到次高组发生冠心病的相对危险分别减少了约 75 % (P<0 .0 5 ) ,41% ,2 2 %。对脑血栓而言 ,最高组与最低组没有差别 ,但收缩压、舒张压的相对危险度都为 1.0 2 7,收缩压 P值为 0 .0 48,舒张压没有差别。胆固醇各组与最高组相比 ,脑出血的死亡相对危险度分别是 2 .3(P=0 .0 5 0 6 ) ,1.72 ,1.13;舒张压的相对危险度 1.0 5 8(P<0 .0 1)。其它疾病相? Objective: To analyze the relationship between cholesterol and coronary heart disease, cerebral thrombosis, cerebral hemorrhage, tumor, cardiovascular and cerebrovascular diseases and other diseases besides tumor. METHODS: Baseline surveys of cardiovascular and cerebrovascular diseases were conducted in 1974, 1979, and 1980 in a group of 4814 male workers aged 18 to 74 years (average 45.3 years) in three groups in a steel plant in Beijing. Serum total cholesterol levels. The end point of follow-up was 1993 and the average follow-up was 14.5 years. Baseline serum cholesterol levels were divided into four groups by the percent quartile method. Using logistic regression analysis, control variables were: age, smoking, alcohol consumption, systolic blood pressure, and diastolic blood pressure. Result: A total of 35 workers died. The causes of death were coronary heart disease 40 (11.4%), cerebral thrombosis 23 (6.55%), cerebral hemorrhage 47 (13.39%), tumor 12 7 (36.18%), other diseases 114 Name (32.48%). The total mortality of the disease was U-shaped with each group of cholesterol. Using the highest cholesterol group as a reference, L ogistic analysis showed that the risk of coronary heart disease mortality was lower in the other cholesterol groups than in the highest group, and the relative risk of coronary heart disease from the lowest group to the second highest group was reduced by about 75% (P < .0, respectively). 5), 41%, 22%. For cerebral thrombosis, there was no difference between the highest group and the lowest group, but the relative risk of systolic blood pressure and diastolic blood pressure was 1.02 7. The systolic blood pressure P value was 0.048, and there was no difference in diastolic blood pressure. Compared with the highest group, the relative death risk of cerebral hemorrhage in each group was 2.3 (P=0.05), 1.72, 1.13; and the relative risk of diastolic blood pressure was 1.058 (P<0. 0 1). Other diseases?
其他文献
目的探讨上海部分地区乳腺癌患者组织中ER、PR、HER-2、PCNA、P53的表达情况,并分析其表达与乳腺癌临床病理的关系。方法采用免疫组织化学方法 ,检测本地区544例乳腺癌组织中
《新民晚报》6月24日B36版“夜光杯”栏刊有《贝加尔湖水自北来》一文,文中说俄罗斯主动向中国表示引贝加尔湖水经 “Xinmin Evening News” on June 24 B36 version of the
请下载后查看,本文暂不支持在线获取查看简介。 Please download to view, this article does not support online access to view profile.
请下载后查看,本文暂不支持在线获取查看简介。 Please download to view, this article does not support online access to view profile.
期刊
由海南省三亚市委宣传部举办的“赞美三亚”歌曲征集评选活动结果日前揭晓。本次征歌活动得到全国各地音乐爱好者的积极响应,共收到来自全国30个省、自治区、直辖市应征歌曲7
数学概念是初中数学的重要基础,也是数学学习的重要环节,没有扎实的概念基础,就没有进一步的深造和提高。本文从把握知识内在联系、通过类比和观察以及生活中引实例等方面,对
恶性血液病患儿化疗后常伴有免疫功能低下、中性粒细胞减少等骨髓抑制表现,是深部真菌感染的高危人群。恶性血液病患儿化疗后深部真菌感染呈现逐年上升趋势,是儿童恶性血液系
《潘朵拉》张韶涵 2006.1《潘朵拉》延续《欧若拉》童话式游戏化的声音,并加入了更多电子和摇滚的元素。其中特地有一首为网络游戏代言的《惊天动地》,还有为OLAY代言的《香
日本在确保围产期的母婴安全方面 ,出台了相应的一系列围产期医疗制度 ,充分认识到母体搬运的重要性。重点介绍母体搬运的目的 ,适应胎儿、适应母婴、适应母体急救以及分娩后
请下载后查看,本文暂不支持在线获取查看简介。 Please download to view, this article does not support online access to view profile.