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本文采用一种新的简易血清唾液酸检测法——F—8836化学比色法对肝癌67例,胆囊癌7例、胰头癌4例,急慢性肝炎72例、重症肝炎28例、肝硬化44例进行检测,并对癌症组以AFP作对照观察。本法检测肝癌阳性率86.5％,用AFP检测阳性率为64.2％(二者相比,P<0.001)。11例胆胰癌,用本法检测全部为阳性,而用AFP检测均为阴性。说明本法可作为诊断肝癌的一种新指标。通过对肝癌、重症肝炎、肝硬化、急慢性肝炎连续动态监测可提高肝癌诊断的阳性率(达到95.5％),并排除假阳性或假阴性。吸光度与病情严重程度呈正比;与疗效成反比,有利于观察疗效、判断预后和转归。
This article uses a new simple serum sialic acid detection method - F-8836 chemical colorimetry for 67 cases of liver cancer, gallbladder cancer in 7 cases, 4 cases of pancreatic cancer, 72 cases of acute and chronic hepatitis, 28 cases of severe hepatitis, cirrhosis Forty-four patients were tested and AFP was used as a control for the cancer group. The positive rate of liver cancer detected by this method was 86.5%, and the positive rate by AFP was 64.2% (P<0.001 for both). In 11 cases of pancreatic and pancreatic cancer, all were positive by this method, but all were negative by AFP. This method can be used as a new indicator for the diagnosis of liver cancer. Continuous monitoring of liver cancer, severe hepatitis, cirrhosis, and acute and chronic hepatitis can increase the positive rate of diagnosis of liver cancer (95.5%), and eliminate false positive or false negative. Absorbance is proportional to the severity of the disease; inversely proportional to the effect, it is beneficial to observe the efficacy, determine the prognosis and outcome.