变应性鼻炎(allergic rhinitis,AR)是耳鼻咽喉科的最常见病之一,其流行情况逐年增加。根据流行病学报告示AR在全世界的发病率为5%~50%~([1]),在中国各大都市经调查显示AR的发病率较高,为8.7%~24.1%~([2])。全球变应性鼻炎的患病率增加,空气污染已被确定为一个导致这一趋势的潜在因素,但潜在的化学机制仍不清楚。空气污染物可以直接影响免疫系统,例如诱导炎症或氧化 Allergic rhinitis (AR) is one of the most common diseases of otorhinolaryngology, its prevalence is increasing year by year. The incidence of AR in the world is 5% ~ 50% ~ ([1]) according to the epidemiological report. The survey of major cities in China shows that the incidence of AR is high, ranging from 8.7% to 24.1% ~ ([2 ]). The prevalence of global allergic rhinitis has increased and air pollution has been identified as a potential contributor to this trend, but the underlying chemical mechanisms remain unclear. Air pollutants can directly affect the immune system, for example, to induce inflammation or oxidation