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摘要目的探讨脑MRI诊断那他珠单抗(NTZ)相关无症状进行性多灶性白质脑病(PML)的准确性、最具预测价值的MRI特征以及与之前数据进行比较的附加值。材料与方法本研究为回顾性研究,获得机构伦理委员会的批准,所有病人均签署知情同意书。11例连续的确诊为无症状NTZ相关PML(NTZ PML,18处脑病灶)的多发性硬化(MS)病人进
Abstract Objective To investigate the accuracy of brain MRI in diagnosing asymptomatic progressive multifocal encephalopathy (PML) associated with natalizumab (NTZ), the most predictive MRI features and the added value compared with the previous data. Materials and Methods This study was retrospectively reviewed and approved by the Institutional Ethics Committee. All patients signed informed consent. Eleven consecutive patients with multiple sclerosis (MS) who were diagnosed as asymptomatic NTZ-associated PML (NTZ PML, 18 brain lesions)