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107例中、重度高血压病人接受双氢克尿塞、心得安及肼苯达嗪等药按方案式梯阶治疗达八年。其中41％病人用第一阶梯药物、51％用第二阶梯、8％以第三阶梯治疗,均控制血压于正常或接近正常水平。阶梯的选择与血压的高度及年龄有关,与高血压分期无明确关系。本文证实有效的降压治疗可逆转已肥大的左心室,并对长期服用双氢克尿塞所致高尿酸血症进行了讨论。
107 cases of patients with severe hypertension received hydrochlorothiazide, propranolol and hydralazine and other drugs according to the program ladder for up to eight years. 41% of patients treated with the first ladder drugs, 51% with the second ladder, 8% with the third ladder, all control the blood pressure at normal or near normal levels. The choice of the ladder is related to the height and age of the blood pressure and has no clear relation to the stage of the hypertension. This article demonstrates that effective antihypertensive therapy can reverse hypertrophied left ventricular and discusses the long-term use of hydrochlorothiazide-induced hyperuricemia.