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To assess the value of scintimammography with both 99m TC-MIBI and 99m Tc-MDP in detecting breast cancer. Methods A total of 35 women with clinical findings of suspicious breast lesions were studied with both 99m Tc MIBI and 99m Tc-MDP scintimammography. All patients underwent surgery within one week and the finaldiagnostic results (histopathological) were obtained. Results Eighteen of 35 abnormalities of breast were pathologically confirmed as breast cancer and 17 as benign lesions. In this group of patients studied, the sensitivity, specificity and accuracy of 99m Tc-MIBI scintimammography were 77. 8%, 88.2% and 82.9%, respectively and those of 99m TC-MDP scintimammography were 72.2%, 88.2% and 80.0%, respectively. There was no significant difference between 99m TC-MIBI and 99m Tc-MDP scintimammography.Conclusion This study showed the high diagnostic accuracy of both 99m TC-MIBI and 99m TC-MDP scintimammography in detecting breast cancer. Both can be used as non-invasively assess breast cancer invasiveness before surgery.
To assess the value of scintimammography with both 99m TC-MIBI and 99m Tc-MDP in detecting breast cancer. Methods A total of 35 women with clinical findings of suspicious breast lesions were studied with both 99m Tc MIBI and 99m Tc-MDP scintimammography. All patients underwent surgery within one week and the final diagnosis of histopathology (histopathological) were obtained. Results of Eighteen of 35 abnormalities of breast were pathologically confirmed as breast cancer and 17 as benign lesions. In this group of patients studied, the sensitivity, specificity and accuracy of 99m Tc-MIBI scintimammography were 77. 8%, 88.2% and 82.9%, respectively and those of 99m TC-MDP scintimammography were 72.2%, 88.2% and 80.0%, respectively. There was no significant difference between 99m TC-MIBI and 99m Tc -MDP scintimammography.Conclusion This study showed the high diagnostic accuracy of both 99m TC-MIBI and 99m TC-MDP scintimammogra phy in detecting breast cancer. Both can be used as non-invasively assess breast cancer invasiveness before surgery.