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目的分析妊娠期特发性血小板减少性紫癜产妇临床特征及治疗效果。方法对2011年7月-2012年8月我院25例妊娠合并特发性血小板减少性紫癜产妇进行回顾性分析,根据不同血小板计数给予不同治疗方法,观察疗效。结果特发性血小板减少性紫癜产妇与正常产妇产后出血及新生儿Apgar评分比较差异无统计学意义(P>0.05);而特发性血小板减少性紫癜产妇阴道产比例低于正常产妇,差异有统计学意义(P<0.05)。治疗后轻度血小板降低产妇,显效4例,有效1例;中度血小板降低产妇显效8例,有效7例,良好1例;重度血小板降低产妇,有效2例,良好2例。结论泼尼松、丙种球蛋白及血小板悬液治疗妊娠合并特发性血小板减少性紫癜产妇效果显著,患者血小板计数均有所上升,且不影响新生儿质量。
Objective To analyze the clinical characteristics and therapeutic effect of pregnant women with idiopathic thrombocytopenic purpura during pregnancy. Methods From July 2011 to August 2012, 25 pregnant women with idiopathic thrombocytopenic purpura in our hospital were retrospectively analyzed. Different treatment methods were given according to different platelet counts to observe the curative effect. Results There was no significant difference between idiopathic thrombocytopenic purpura and postpartum hemorrhage and neonatal Apgar score in idiopathic thrombocytopenic purpura (P> 0.05). However, the proportion of vagina in idiopathic thrombocytopenic purpura was lower than that in normal women Statistical significance (P <0.05). Mild thrombocytopenia after treatment, 4 cases markedly effective in 1 case; moderate thrombocytopenia decreased maternal 8 cases markedly effective in 7 cases, good in 1 case; severe thrombocytopenia maternal, effective in 2 cases, good in 2 cases. Conclusion Prednisone, gamma globulin and platelet suspension treatment of pregnant women with idiopathic thrombocytopenic purpura significantly effect, patients with platelet count increased, and does not affect the quality of newborns.