尿毒症患者及长期血透患者ＮＰ的趋化移动、粘附调理及吞噬杀菌功能受到不同程度的损伤，可能为细胞因素或为体液因素，或二者兼有，ＥＰＯ虽用来治疗肾性贫血，但临床发现其对ＮＰ功能的改善有个进作用，可减少感染发生率，ＥＰＯ在体内对ＮＰ的生成、代谢及功能影响尚需深入探讨 In patients with uremia and long-term hemodialysis patients with NP chemotaxis migration, adhesion regulation and phagocytosis have varying degrees of damage, may be cytokines or humoral factors, or both, although the EPO is used to treat renal anemia , But it is clinically found that it has an effect on the improvement of NP function, which can reduce the incidence of infection and the effect of EPO on the formation, metabolism and function of NP in vivo.