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疏水性是细菌粘附到宿主表面能力的一个重要组织部分。本研究旨在通过疏水性分析了解三种变形链球菌菌株的粘附力及0.005%洗必泰液和1000ppm氟溶液对疏水性的影响。实验采用hexadacane法对疏水性进行测定。结果发现:S.mutansTK18.Em—2的疏水性与S.mutansMT8148的疏水性有显著性差异(P<0.05),0.005%洗必泰能显著改变S.mutansMT8148.TK18的疏水性(P<0.05),而1000ppm的氟溶液则对三种菌的疏水性均无显著性影响(P>0.05)。本实验提示;表面蛋白(特指表面蛋白抗原PAC)是疏水性强弱的决定因素之一。洗必泰可改变变形链球菌的疏水性,这可能是其防龋的机理之一。氟溶液则不同于此机理。
Hydrophobicity is an important part of the ability of bacteria to adhere to host surfaces. The aim of this study was to understand the effect of three Streptococcus mutans adhesion on hydrophobicity by hydrophobic analysis and 0.005% chlorhexidine solution and 1000 ppm fluorine solution. Hydrophobicity was determined by hexadacane method. The results found: mutansTK18. The hydrophobicity of Em-2 and S. The hydrophobicity of mutansMT8148 was significantly different (P <0.05), 0.005% chlorhexidine can significantly change the S. mutansMT8148. TK18 hydrophobicity (P <0.05), while the 1000ppm fluoride solution had no significant effect on the hydrophobicity of three kinds of bacteria (P> 0.05). The experimental tips; surface proteins (especially surface antigen PAC) is one of the determinants of hydrophobicity. Chlorhexidine can change the hydrophobicity of Streptococcus mutans, which may be one of its anti-caries mechanism. Fluorine solution is different from this mechanism.