目的探索玉溪市伤寒/副伤寒流行危险因素,为制定针对性控制方案提供科学依据。方法对玉溪市700例伤寒/副伤寒病例按照1:1配比,采用病例对照方法进行研究分析。结果不同流行强度区域,差异有统计学意义的危险因素各不相同,高流行区为经常在外就餐(χ2=8.28,P﹪0.05 OR=1.68)、经常吃凉菜(χ2=6.78,P﹪0.05)和经常吃烧烤(χ2=4.27,P﹪0.05),中流行区为经常饮用生水(χ2=21.99,P﹪0.05)、经常饮井水(χ2=17.35,P﹪0.05),低流行区为有接触史(χ2=10.06,P﹪0.05)、经常饮用生水(χ2=11.81,P﹪0.05)和经常饮井水(χ2=10.06,P﹪0.05)。结论玉溪市伤寒/副伤寒不同流行区域主要流行危险因素不同,高流行区流行危险因素是经常在外就餐、经常吃凉菜和经常吃烧烤,中流行区的流行危险因素是经常饮用生水、井水,低流行区的危险因素是接触史、经常饮用生水、井水。因此根据不同区域,采取差异化防控措施是必要和可行的。 Objective To explore epidemiological risk factors of typhoid / paratyphoid in Yuxi City, and to provide a scientific basis for formulating targeted control programs. Methods 700 cases of typhoid / paratyphoid in Yuxi City were allocated according to the ratio of 1: 1, and the case-control method was used to analyze and analyze them. Results There were statistically significant differences in risk factors among different prevalence intensity areas. High prevalence areas were often out-of-house meals (χ2 = 8.28, P% 0.05 OR = 1.68) (Χ2 = 4.27, P% 0.05). In the endemic area, drinking regular water (χ2 = 21.99, P% 0.05), drinking well water frequently (χ2 = 17.35, P% There was a history of exposure (χ2 = 10.06, P% 0.05). Regular drinking of raw water (χ2 = 11.81, P% 0.05) and regular drinking water (χ2 = 10.06, P% Conclusions The main epidemic risk factors are different in different endemic areas of typhoid / paratyphoid in Yuxi. The epidemic risk factors in high endemic areas are often eating outside, often eating cold dish and often eating barbecue. The prevailing risk factors in endemic areas are regular consumption of raw water and well water The risk factors for low endemic areas are exposure history, frequent drinking of raw water and well water. Therefore, according to different regions, to take differentiated prevention and control measures is necessary and feasible.