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CS-807是一种新的口服头孢菌素R-3746的前药,其化学结构如下图所示.本文报道CS-807、R-3746对临床分离菌株的体外抗菌活性、杀菌作用和体内保护
CS-807 is a new prodrug of oral cephalosporin R-3746 and its chemical structure is shown in the following figure.We report the in vitro antibacterial activity, bactericidal activity and in vivo protection of CS-807 and R-3746 against clinical isolates