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目的探究神经节苷脂治疗急性脑出血的疗效。方法选取110例急性脑出血患者作为研究对象,将其随机均等分成2组,每组55例。对照组采用胞磷胆碱进行治疗,试验组在对照组的基础上配合使用40~60 mg的神经节苷脂注射液加入250 m L的生理盐水中进行静脉滴注,1次/d,14 d为1个疗程。利用NIHSS(美国国立卫生研究院卒中量表)评分对患者的神经功能损伤进行评判,利用ADL(日常生活活动能力)评分对患者的日常生活的生活能力进行评判,比较2组治疗有效率和NIHSS、ADL评分的高低。结果治疗后,试验组显效34例,有效18例,无效3例,治疗总有效率为94.5%;对照组显效显效18例,有效28例,无效9例,治疗有效率为83.6%。试验组的治疗有效率高于对照组,差异有统计学意义(P<0.05)。结论神经节苷脂能有效治疗急性脑出血,帮助患者恢复日常生活能力,疗效显著,具有推广应用价值。
Objective To explore the efficacy of ganglioside in the treatment of acute cerebral hemorrhage. Methods A total of 110 patients with acute cerebral hemorrhage were selected as subjects and randomly divided into two groups (55 in each group). The control group was treated with citicoline, and the experimental group was treated with 40-60 mg ganglioside injection in 250 ml normal saline on the basis of the control group, once a day, 14 times a day d for a course of treatment. The NIHSS score was used to evaluate the neurological impairment and the ADL (daily living activity) score was used to evaluate the daily living ability of the patients. The treatment efficiency and NIHSS , The level of ADL score. Results After treatment, the experimental group markedly effective in 34 cases, effective in 18 cases, 3 cases, the total effective rate was 94.5%; the control group markedly effective in 18 cases, effective in 28 cases, ineffective in 9 cases, the effective rate was 83.6%. The treatment group was higher than the control group, the difference was statistically significant (P <0.05). Conclusion Gangliosides can effectively treat acute intracerebral hemorrhage and help patients to recover their daily living ability. The curative effect is significant and has the promotion and application value.