颅脑损伤是常见的神经外科急症。在高原地区由于受到低温、低氧、低气压等特殊环境影响,颅脑损伤后病情往往发展更加迅速。随着海拔高度的升高,病情也随之加重。中性粒细胞弹性蛋白酶(NE)在颅脑损伤后表达水平增高,且与损伤程度 Craniocerebral injury is a common neurosurgical emergency. Due to the special environment of low temperature, hypoxia and low pressure in the plateau, the disease tends to develop more rapidly after head injury. As the altitude increases, the condition also aggravates. Neutrophil elastase (NE) expression increased after traumatic brain injury, and with the degree of injury