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目的分析原发性泪腺上皮性肿瘤的组织病理学特征与复发的关系,为临床诊治提供参考。方法收集128例病理诊断为原发性泪腺上皮性肿瘤患者的石蜡标本,其中最常见的三种依次为良性混合瘤74例(57．8％),腺样囊性癌22例(17．2％),恶性混合瘤18例(14．1％),分析其组织病理学特征与复发的关系。结果良性混合瘤、腺样囊性癌和恶性混合瘤的复发率分别为23．0％、18．2％和27．8％。其中良性混合瘤的病理类型和包膜完整性在肿瘤的复发中具有统计学意义。结论三种常见原发性泪腺上皮性肿瘤复发率高,了解其病理表现对肿瘤的诊断、治疗方式的选择和随访时间的确定具有参考意义。
Objective To analyze the relationship between histopathological features and recurrence of primary lacrimal gland epithelial tumor and provide reference for clinical diagnosis and treatment. Methods A total of 128 paraffin-embedded specimens from patients diagnosed as primary lacrimal gland epithelial tumor were collected, of which 74 were benign mixed tumors (57.8%), 22 were adenoid cystic carcinomas (17.2 %), Malignant mixed tumor in 18 cases (14.1%), analyze the relationship between the histopathological features and recurrence. Results The recurrence rates of benign mixed tumor, adenoid cystic carcinoma and malignant mixed tumor were 23.0%, 18.2% and 27.8% respectively. Among them, benign mixed tumor pathological types and envelope integrity in the recurrence of tumors with statistical significance. Conclusion The recurrence rates of three common primary lacrimal gland epithelial tumors are high. It is of reference significance to understand the pathological manifestation of tumor diagnosis, treatment options and follow-up time.