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LACA小鼠腹腔注射HPD 0.4mg、2.0mg和2.0mg×3/只后,免疫器官都发生不同程度的组织学效应。主要为胸腺萎缩,脾和淋巴结(肠系膜)的胸腺依赖区萎缩及其中淋巴细胞减少;脾白髓边缘区内淋巴细胞减少或消失,淋巴滤泡萎缩,滤泡内中、小淋巴细胞对HPD的反应比生发中心细胞更明显。牌生发中心数量减少和截面积变小。文中强调,这些代表T、B淋巴细胞系统的组织结构变化,必然会影响或有损机体的细胞和体液免疫功能。
LACA mice were injected intraperitoneally with HPD 0.4mg, 2.0mg and 2.0mg × 3 / only, the immune organs have varying degrees of histological effects. Mainly thymus atrophy, spleen and lymph node (mesenteric) thymus-dependent zone of atrophy and lymphopenia; marginal zone of spleen white pulp lymphocytes decreased or disappeared, follicular atrophy, follicular, small lymphocytes to HPD Reactions more pronounced than germinal center cells. Card hair growth and reduce the number of cross-sectional area smaller. The article stressed that these representatives of T, B lymphocyte system changes in the organizational structure, will inevitably affect or damage the body’s cellular and humoral immune function.