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目的 探讨并总结多弹头射频治疗肝癌的临床近期疗效。方法 对 31例肝癌患者在B超引导下进行多弹头射频治疗 ,通过对手术前后CT、B超检查的比较及AFP、肝功能、机体免疫力、体重和自觉症状的改变进行对比观察。结果 31例于治疗后 7天、1 0例于治疗后 30天经B超及CT检查 :7天后 80 %的病人肿瘤体积缩小 30 %以上 ,30天后 1 0例病人肿瘤体积缩小 40 %以上 ,与术前相比瘤体内血供消失。 84%病人自觉症状改善 ,AFP值下降者占 77 8% ,肝功能酶谱及胆红素均恢复正常 ,白蛋白平均增加 1 1 0 g/L。体重增加 5 6kg ,T淋巴细胞转化率平均增加 2 1 %。IgG平均增加 2 0 g/L ,无手术死亡。结论 多弹头射频治疗肝癌的适应证广、安全可靠、疗效满意
Objective To explore and summarize the clinical short-term efficacy of multi-warhead radiofrequency ablation for liver cancer. Methods Thirty-one patients with hepatocellular carcinoma underwent multi-warhead radiofrequency treatment guided by B-ultrasound. The comparison of CT and B-ultrasound before and after surgery and the changes of AFP, liver function, body immunity, body weight and subjective symptoms were compared. RESULTS: Thirty-one patients were diagnosed by ultrasound and CT at 7 days after treatment and 10 at 30 days after treatment. After 7 days, the tumor volume was reduced by more than 30% in 80% of the patients. After 30 days, the tumor volume was reduced by more than 40% in 10 patients. The blood supply to the tumor disappeared before surgery. 84% of patients improved their subjective symptoms, and the AFP value decreased 77.8%. The liver function zymogram and bilirubin returned to normal and albumin increased by an average of 110 g/L. With a weight gain of 5 6 kg, the T-lymphocyte conversion rate increased by an average of 21%. The average increase in IgG was 20 g/L, with no operative mortality. Conclusion Multi-warhead radiofrequency treatment for liver cancer has wide indications, safety, and satisfactory results