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在慢性乙型肝炎的干扰素治疗中,下列一些指标可预示具有疗效:HBV DNA<200pg/ml、ALT<100IU/L、女性、感染时期短、抗HIV阴性、异性恋和非亚裔者。而慢性丙型肝炎则无明确的治疗反应预示指标。因而慢性丙肝的治疗原则比乙肝更复杂。干扰素在慢性乙肝和丙肝的治疗中证实是有效果的抗病毒剂,通过测定HBV DNA和HCV RNA以监测疗效可为慢性乙肝和丙肝的治疗提供更合理的决策。 慢性乙型肝炎:干扰素每日1次,每次5百万单位(MU),或每周3次,每次10MU,疗程4个月。治疗后如HBV DNA消失和转氨酶恢复正常,可无需再治疗。
In the treatment of chronic hepatitis B interferon, the following indicators may indicate the curative effect: HBV DNA <200pg / ml, ALT <100IU / L, women, short duration of infection, anti-HIV negative, heterosexual and non-Asians. The chronic hepatitis C is no clear indication of treatment response. Thus the principle of treatment of chronic hepatitis C more complicated than hepatitis B. Interferon has proven to be an effective antiviral in the treatment of chronic hepatitis B and C, and monitoring HBV efficacy by measuring HBV DNA and HCV RNA can provide more informed decisions on the treatment of chronic hepatitis B and C. Chronic hepatitis B: Interferon once daily, 5 million units (MU), or 3 times a week, each 10MU, treatment for 4 months. After treatment such as the disappearance of HBV DNA and transaminases returned to normal, no need for further treatment.