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胆管癌术前的定性诊断十分困难。检测胆汁肿瘤标志物是一条可研究的途径。本文探讨胆汁癌胚抗原(CEA)和糖类抗原72-4(CA_(72-4))联合检测对胆管癌的诊断价值。 1.材料和方法:研究对象来自本院自1999年1月至2002年4月收治的66位病人,胆管癌32例(男20例,女12例),胆管良性病变34例(男15例,女19例)。术前经ENBD或PTCD、术中直接穿刺胆管收集胆汁。经超速离心15 min后,取上清液5 ml,—20℃存放。
Preoperative diagnosis of cholangiocarcinoma is very difficult. Detection of bile tumor markers is a researchable route. This article discusses the diagnostic value of combined detection of bile carcinoembryonic antigen (CEA) and carbohydrate antigen 72-4 (CA_(72-4)) for cholangiocarcinoma. 1.Materials and methods: The subjects were 66 patients who were admitted to our hospital from January 1999 to April 2002. There were 32 cases of cholangiocarcinoma (20 males and 12 females). There were 34 cases of benign bile duct lesions (15 males). , female 19 cases). Bile was collected by direct intraoperative puncture of bile ducts by ENBD or PTCD before surgery. After ultracentrifugation for 15 min, take 5 ml supernatant and store at -20°C.