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目的为了解赤峰市疑似预防接种异常反应(AEFI)发生情况,评价AEFI监测系统运转状况及疫苗的安全性。方法采用描述性流行病学方法对监测资料进行分析。结果赤峰市2009年共报告AEFI个案119例,其中一般反应占84.87%,异常反应占14.29%,心因性反应占0.84%。1岁以下病例占50.42%,81.51%的AEFI发生在接种后24h内。一般反应中最常见的是发热、红肿、硬结(97.03%),异常反应中最常见的是过敏性皮疹(58.82%)。结论 AEFI监测系统总体运转情况良好,疫苗安全性高,须进一步完善AEFI鉴定补偿办法,加强相关人员AEFI知识培训,提高AEFI监测工作质量。
Objective To understand the occurrence of suspected AEFI in Chifeng City and evaluate the operational status of AEFI monitoring system and the safety of the vaccine. Methods Descriptive epidemiological methods were used to analyze monitoring data. Results A total of 119 AEFI cases were reported in Chifeng City in 2009, of which 84.87% were general reactions, 14.29% were abnormal reactions and 0.84% were cardiorestrual reactions. Cases under 1 year old accounted for 50.42%, 81.51% of AEFI occurred within 24 hours after inoculation. The most common reaction is fever, redness, induration (97.03%), the most common anaphylactic reaction is allergic rash (58.82%). Conclusion The overall operation of AEFI monitoring system is good and the safety of the vaccine is high. AEFI identification and compensation measures need to be further perfected, training of AEFI knowledge of relevant personnel should be strengthened, and the quality of AEFI monitoring should be improved.