脑微循环血流速度的测定,不仅在探讨缺血性脑卒中与脑微循环血流速度的关系方面,而且在寻求有关药物的过筛方面,都具有重要意义。目前国内外对脑微循环的活体观察,常规方法是颅骨开窗,切开硬膜后观察软脑膜血管。但这种开放颅骨的方法,可使软脑膜血管变细,明显影响血流速度。我们采用不开颅骨直接测定的方法,观测脑膜血管血流速度效果颇为满意,现介绍如下。 Determination of cerebral microcirculation blood flow velocity, not only in the discussion of ischemic stroke and cerebral microcirculation flow velocity relationship, but also in the search for the screening of drugs, are of great significance. At present, the observation of brain microcirculation in vivo at home and abroad, the conventional method is to open the window of the skull and cut the dura to observe the pial vessels. However, this method of opening the skull, can make the pia mater blood vessels thin, significantly affect the blood flow velocity. We do not open the skull direct measurement method to observe the effect of blood flow velocity of meningeal blood is quite satisfactory, are presented below.